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Similar words: Firearms  France  Furans  Ferns  Frankia  

Neuropilin-2

NRP2 Protein | Npn-2 Protein | Neuropilin 2 | Npn 2 Protein

Transmembrane receptor for CLASS 3 SEMAPHORINS and several vascular endothelial growth factor isoforms. Neuropilin-2 functions either as a homodimer or as a heterodimer with NEUROPILIN-1. The binding affinity of neuropilin-2 varies for different class 3 semaphorin isoforms and is dependent on the composition of the dimer. The protein also forms receptor complexes with plexins and with VEGF RECEPTORS, which alters the binding characteristics of the receptor.

Dosage Forms

Dosage Form | Form, Dosage | Forms, Dosage

Completed forms of the pharmaceutical preparation in which prescribed doses of medication are included. They are designed to resist action by gastric fluids, prevent vomiting and nausea, reduce or alleviate the undesirable taste and smells associated with oral administration, achieve a high concentration of drug at target site, or produce a delayed or long-acting drug effect. They include CAPSULES; LINIMENTS; OINTMENTS; PHARMACEUTICAL SOLUTIONS; POWDERS; TABLETS; etc.

Suppositories

Rectal Suppositories | Vaginal Suppositories | Vaginal Suppository | Suppositories, Rectal | Suppositories, Vaginal | Suppository, Vaginal

Medicated dosage forms that are designed to be inserted into the rectal, vaginal, or urethral orifice of the body for absorption. Generally, the active ingredients are packaged in dosage forms containing fatty bases such as cocoa butter, hydrogenated oil, or glycerogelatin that are solid at room temperature but melt or dissolve at body temperature.

Hematologic Neoplasms

Hematologic Malignancies | Hematopoietic Neoplasms | Hematologic Malignancy | Hematological Malignancies | Hematological Neoplasms | Hematopoietic Malignancies | Malignancies, Hematologic | Malignancy, Hematologic | Neoplasms, Hematologic

Neoplasms located in the blood and blood-forming tissue (the bone marrow and lymphatic tissue). The commonest forms are the various types of LEUKEMIA, of LYMPHOMA, and of the progressive, life-threatening forms of the MYELODYSPLASTIC SYNDROMES.

Ichthyosiform Erythroderma, Congenital

Congenital Ichthyosiform Erythroderma | Congenital Ichthyosiform Erythroderma, Dry Type | Congenital Ichthyosiform Erythroderma, Wet Type | Erythroderma, Congenital Ichthyosiform | Congenital Ichthyosiform Erythrodermas

Designation for several severe forms of ichthyosis, present at birth, that are characterized by hyperkeratotic scaling. Infants may be born encased in a collodion membrane which begins shedding within 24 hours. This is followed in about two weeks by persistent generalized scaling. The forms include bullous (HYPERKERATOSIS, EPIDERMOLYTIC), non-bullous (ICHTHYOSIS, LAMELLAR), wet type, and dry type.

Gaucher Disease

Cerebroside Lipidosis Syndrome | Glucocerebrosidase Deficiency Disease | Glucosylceramide Beta-Glucosidase Deficiency Disease | Neuronopathic Gaucher Disease | Acute Neuronopathic Gaucher Disease | Chronic Gaucher Disease | Gauchers Disease

An autosomal recessive disorder caused by deficiency of the enzyme glucocerebrosidase (see GLUCOSYLCERAMIDASE) featuring the pathological storage of glycosylceramide in mononuclear PHAGOCYTES (Gaucher Cells). The most common subtype is the non-neuronopathic form, a slowly progressive condition characterized by hepatosplenomegaly and skeletal deformities. The neuronopathic forms are divided into infantile and juvenile forms. The infantile form presents at 4-5 months of age with anemia, loss of cognitive gains, neck retraction, dysphagia, and hepatosplenomegaly. The juvenile form features a slowly progressive loss of intellect, hepatosplenomegaly, ATAXIA, myoclonic SEIZURES, and spasticity. The neuronopathic forms are characterized by neuronal loss with neuronophagia, and accumulation of glucocerebroside in neurons. (From Baillieres Clin Haematol 1997 Dec;10(4):711-23; Menkes, Textbook of Child Neurology, 5th ed, p97)

Keratin

Cytokeratin | Cytokeratin 13 | Cytokeratin 16 | Cytokeratin 17 | Cytokeratin 18 | Cytokeratin 19 | Cytokeratin 4 | Cytokeratin 8 | Cytokeratin 9 | Cytokeratin D | Cytokeratin Hax | Cytokeratin Hbx | Endo-A Cytokeratin | Endo-A Protein | Endo-B Cytokeratin

A class of fibrous proteins or scleroproteins important both as structural proteins and as keys to the study of protein conformation. The family represents the principal constituent of epidermis, hair, nails, horny tissues, and the organic matrix of tooth enamel. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms an alpha-helix, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure.

Pituitary Neoplasms

Pituitary Tumors | Neoplasm, Pituitary | Neoplasms, Pituitary | Pituitary Neoplasm | Pituitary Tumor | Tumor, Pituitary | Tumors, Pituitary

Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.

Paleontology

The study of early forms of life through fossil remains.

Streptomycetaceae

A family of soil bacteria. It also includes some parasitic forms.
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